The Dutch side will no doubt be in hopes of keeping their perfect correct score intact in the Dutch league this weekend as they host PEC Zwolle at Philips Stadion in a gameweek 10 fixture.
The hosts remain the only team in the division that hasn't dropped a single point this season, while the visitors have picked up just eight points in the first nine games of the campaign.
PSV return to domestic action after a Champions League outing on Wednesday in which they fought their way to a valuable draw against Paris Saint-Germain in matchweek three.
That would mean the Red and Whites have still been searching for their first victory in the European championship this term, they do not have a similar problem in their domestic league after managing to string nine league victories together.
The last league victory was a week ago as they traveled and squeezed past AZ Alkmaar 2-1; the Farmers extended their aggregate league points total this campaign to 29-five ahead of any other team.
Notably, Peter Bosz's men have scored two or more goals in all nine top-flight games this term and each of their last eight in Eindhoven, where they secured their only other clean sheet to date - a 1-0 victor against Twente - back in mid-March.
The last time PSV Eindhoven lost a League match at the Phillips stadium is as old as the hills, it was on the 3 November 2022, 31 consecutive games ago they have been winning 28 and drawing 3.
On the other hand, PEC Zwolle have been an awful side this season and scored only 2 wins in the first nine games, and they are now expecting not to lose two successive matches.
He joins the Portuguese club's injury chart, as Eduardo Quaresma, a 22-year-old defender missed the last two games after getting hurt against Casas Pia just before the international break.
The 24 already goal-scoring Gyokeres this season for club and country will be one to bank on for goals after being involved in both of the goals against Sturm Graz in the middle of the week.
Blauwvingers lost at home to NAC Breda 2-1 last weekend. With that-their fifth defeat of the season-they slipped into a tie with Heerenveen, now in contention for that relegation playoff berth, on eight points.
Johnny Jansen's men will now head back onto the road, where points have been hard to come by, following their failure to win any of their last 11 league games since early February. Given that they have lost 16 in a row to PSV since 2015, and also given the score of 56-11 since then, it is highly unlikely that the visitors will get off the mark with an away win tonight.